Lab Test Interpretation
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CBC and CMP - two common blood tests that often get mixed up. They sound alike, but they check for very different things. One looks at blood cells, the other at organ function and metabolism.
Your doctor can order one or both of these tests to check different aspects of your health
Here’s a simple breakdown of what each test does and when you might need them.
A Complete Blood Count (CBC) is one of the most common blood tests. It checks the health of your blood cells and helps doctors find infections, anemia, or blood disorders.
Your doctor might order this test to monitor your overall health or look for signs of a medical condition.
A Comprehensive Metabolic Panel (CMP) takes a broader look at your health, checking organ function, blood sugar, and electrolyte balance. It helps doctors detect liver and kidney issues, monitor chronic conditions like diabetes, and assess overall metabolic health.
A CBC mainly evaluates the number and quality of your blood cells.s. A CMP, on the other hand, measures your metabolic health and organ function.
CBC Components | CMP Components |
---|---|
Red Blood Cells (RBC) | Glucose (blood sugar) |
White Blood Cells (WBC) | Electrolytes (Sodium, Potassium, Chloride, CO2) |
Hemoglobin (Hb) | Kidney tests (Creatinine, Blood Urea Nitrogen [BUN]) |
Hematocrit (Hct) | Liver tests (ALT, AST, ALP, Bilirubin) |
Platelets | Proteins (Albumin, Total Protein) |
Mean Corpuscular Volume (MCV) | Calcium |
Mean Corpuscular Hemoglobin (MCH) | - |
Mean Corpuscular Hemoglobin Concentration (MCHC) |
- |
Red Cell Distribution Width (RDW) | - |
Mean Platelet Volume (MPV) | - |
CBC often includes a WBC Differential. This shows the levels of different white blood cells, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils. Doctors use this information to identify infections, allergies, or immune-related conditions more precisely.
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A CBC checks your blood cells. Doctors usually order it if you feel tired, have frequent infections, pale skin, or unexplained bruises.
A CMP checks your overall metabolic health, including organ function and electrolytes. It’s typically ordered if you have ongoing fatigue, nausea, changes in urination, or swelling. It also helps to monitor conditions like diabetes or check blood sugar levels.
You usually don't need any special preparation for a CBC.
Before a CMP test, your doctor might ask you to avoid eating, drinking alcohol, or taking certain medications for accurate results.
Feature | CBC | CMP |
---|---|---|
Measures | Blood cells | Metabolic health |
Checks for | Anemia, infection, clotting issues | Organ function, electrolyte balance |
Ordered When | Fatigue, infection, bleeding issues suspected |
Liver/kidney disease, diabetes monitoring |
Symptoms That May Require This Test |
Pale skin, frequent infections, unexplained bruising |
Jaundice, swelling, unusual thirst, frequent urination |
Test Preparation | No special preparation needed | May require fasting; avoid alcohol; check medication use with doctor |
Doctors order both tests when they need a detailed picture of your overall health. A CBC can detect issues like anemia or infections, while a CMP helps assess kidney, liver, and metabolic function. Together, they provide a broader understanding of potential health concerns.
Neither test directly diagnoses cancer, but abnormal results in a CBC could suggest blood cancers like leukemia. A CMP might show liver or kidney abnormalities that could require further testing. If your doctor suspects cancer, they will order additional specialized tests.
Results are usually available within a few hours to a day, depending on the lab. Some clinics may provide same-day results, while others might take a little longer if additional testing is needed.
A doctor may order a BMP instead of a CMP if they only need to check basic metabolic functions, such as kidney health and electrolytes. If liver function is not a concern, a BMP is often enough. However, if a more complete picture of organ function is needed, a CMP is the better choice.
Yes, dehydration can impact both tests. A CBC may show higher hematocrit and hemoglobin levels, while a CMP may indicate imbalances in electrolytes like sodium and potassium. If your results seem off, your doctor may ask you to rehydrate and repeat the test.
This article was written by doctors from the Docus Medical Research team and reviewed by leading experts in hematology and nephrology. As part of our editorial and medical review process, we relied on academic studies, medical research, and publications from credible sources to ensure the information provided is accurate and trustworthy.
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