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Oxalate in urine acts as a biomarker for kidney and metabolic health. Oxalate levels help assess kidney function, detect metabolic issues, and identify dietary influences.
Oxalate in urine, or urinary oxalate, refers to the presence of oxalate compounds that are filtered through the kidneys and excreted in urine.
Oxalate is a natural compound found in many foods and produced by the liver. In the body, oxalate binds with minerals, especially calcium, to form crystals. These oxalate crystals can sometimes build up in the kidneys, potentially leading to kidney stones or other health issues.
Healthcare professionals use urinary oxalate levels as a biomarker to assess kidney function and diagnose specific metabolic or renal conditions.
Tracking oxalate in urine can help manage kidney health, detect dietary issues, and support overall metabolic function.
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Oxalate testing is typically recommended when symptoms of kidney or metabolic conditions are present, or as part of ongoing health monitoring for those at risk.
Oxalate testing may be prescribed in the following situations:
Oxalate levels are measured through a urinalysis that typically involves a 24-hour urine collection. In this test, all urine excreted over a 24-hour period is collected and analyzed in a laboratory. This method provides a more accurate picture of daily oxalate excretion levels. Sometimes, a random urine sample may be taken, though the 24-hour collection is more precise.
Preparation for Oxalate Testing
To prepare for an oxalate urine test, consider the following:
The typical range for urinary oxalate in adults is 0.08-0.49 mmol/L over a 24-hour period.
Note: The units of measurement and normal ranges can differ depending on the laboratory and the specific methods used.
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Abnormal oxalate levels, whether high or low, may indicate underlying health issues or imbalances that require attention.
High levels of oxalate in the urine, known as hyperoxaluria, can have several causes, often indicating metabolic or dietary issues:
Low levels of oxalate in urine are generally uncommon and usually not concerning. However, certain conditions or dietary factors can lead to low oxalate levels.
For concerns about oxalate levels in urine, consult one of the following specialists:
To flush oxalates from the body, increase your water intake to help dilute and remove oxalates through urine. Consuming calcium-rich foods with meals can also bind oxalates in the digestive tract, reducing absorption. Additionally, limit high-oxalate foods like spinach, nuts, and beets. Consult with a healthcare provider for personalized guidance, especially if you have kidney concerns.
High oxalate levels may impact calcium availability, potentially affecting bone density if left unmanaged over time.
Gut health affects oxalate absorption; conditions like IBS or poor gut microbiome health can increase urinary oxalate levels.
This article was written by doctors from the Docus Medical Research team and reviewed by leading urology and nephrology experts. We relied on academic studies, medical research, and publications from credible sources to ensure the information provided is accurate and trustworthy.
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