SC or SQ Medical Abbreviation Explained Simply

Updated on: Jul 04, 2025 | 2 min read

Question on this topic? Get an instant answer from AI Doctor.Instant answer from AI Doctor.

What Does SC or SQ Mean?

SC and SQ are both abbreviations for subcutaneous, which means “under the skin.”

Healthcare workers use these terms when talking about injections given into the fatty tissue just below the skin. You might see SC (more common nowadays) or SQ written on medical instructions or labels.

Both mean exactly the same thing and are used interchangeably, so you don’t need to worry if you see either one.

Where Are SC or SQ Injections Given?

A subcutaneous (SC or SQ) injection goes into the soft layer of fat between your skin and muscles. This area has fewer blood vessels, so the medication absorbs more slowly compared to a muscle injection.

Common areas of the body where these injections are given include:

  • The abdomen (avoiding the belly button area)
  • The front or outer side of the thighs
  • The upper outer part of the arms

These areas are chosen because they have enough fatty tissue and are easy to reach.

Why Are SC or SQ Injections Used?

SC or SQ injections are used because they are simple, effective, and don’t require deep penetration into the body. They allow medications to be absorbed slowly and steadily, which is ideal for some treatments.

Situations where SC/SQ injections are preferred:

  • When a slow and steady release of the medication is needed
  • When the patient can safely give themselves the injection at home

This method is less intimidating than other injection types and is often recommended for ongoing care.

Common Medications Given SC/SQ

Many types of treatments use the SC/SQ route because of its simplicity and effectiveness. These often include:

  • Medications that need to be released slowly over time
  • Medicines that are safe and easy to inject without medical supervision
  • Hormones and other substances that don’t need to go directly into a vein or muscle

This method works well for people managing long-term conditions, offering a convenient way to receive necessary care at home.

How to Administer an SC or SQ Injection

Giving a subcutaneous injection may feel scary at first, but it becomes easier with practice. Here’s a simple step-by-step guide:

  1. Prepare the medication: Check the label, wash your hands, and gather all supplies.
  2. Choose the site: Pick an area with enough fatty tissue and rotate sites each time to avoid irritation.
  3. Clean the skin: Use an alcohol wipe to disinfect the spot and let it dry.
  4. Insert the needle: Pinch the skin gently and insert the needle at about a 45-90 degree angle.
  5. Dispose of supplies safely: Place the used needle in a proper sharps container.

SC vs SQ: Which Term Should You Use?

Both SC and SQ mean the same thing, but some organizations prefer SC because it avoids confusion with other abbreviations.

However:

  • Some people and materials still use SQ, and it’s perfectly fine.
  • Both are widely understood by healthcare professionals, so you can use either without a problem.

If you’re ever unsure, you can simply say “subcutaneous,” and everyone will know what you mean.

Are There Any Other Abbreviations That Mean Subcutaneous?

Besides SC and SQ, you might also see the abbreviation subq in some places.

  • (SUB-Q) subq  - a shortened, informal way of writing subcutaneous.
  • Some older documents or instructions may even spell out Subcut or just Sub.

All of these mean the same thing: an injection given into the fatty layer under the skin.

When learning about SC or SQ, you may also notice other medical abbreviations for different ways medications are given. These show the route the medicine takes in your body:

  • IM Intramuscular: into the muscle.
  • IV Intravenous: directly into a vein.
  • ID Intradermal: just under the surface of the skin, in the top layer.
  • PO Per os: which means “by mouth.” You swallow the medicine.
  • SL Sublingual: placed under the tongue, where it dissolves and enters the bloodstream.
  • PR Per rectum: given through the rectum
AI Assistant

Have Questions?

Have a question on this topic? Submit it here and get an instant answer from our AI Doctor.

Please Note!This tool is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult a professional before taking any action.

Make Informed Health Decisions

Talk to Docus AI Doctor, generate health reports, get them validated by Top Doctors from the US and Europe.

Make Informed Health Decisions

You’re only one click away from a life-changing journey

Virtual health assistant powered by AI
350+ world-renowned Doctors