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Healthcare notes are filled with abbreviations, and R/O is one you’ll often see. Doctors and nurses use it to describe their thought process when diagnosing a patient.

It means the healthcare provider suspects a possible condition and wants to test or monitor to confirm or eliminate it.
For example:
R/O shows that a condition is under consideration, not yet proven or dismissed.
You’ll find R/O in:
It’s an essential part of clinical reasoning and helps guide which tests or imaging are ordered.
R/O helps communicate uncertainty in a structured way. It tells other clinicians which conditions are being considered and what needs to be confirmed.
For example:
This documentation supports teamwork and safe decision-making.
The American College of Physicians notes that accurate documentation of working and differential diagnoses is vital for proper evaluation and treatment. R/O helps make that process clear and transparent.
R/O can be confused with other diagnostic abbreviations:
For example, a note might read:
“Cough and fever - R/O pneumonia. Pending chest X-ray to confirm Dx.”

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